Parathyroid cysts (PC) are a rare cause of neck masses, with an ectopic intrathyroidal location being even rarer. Join endocrine experts Victor J. Bernet, MD, FACE, FACP, Director, Endocrinology, Diabetes and Metabolism Fellowship Program at the Mayo Clinic in Florida, and Sina Jasim, MD, MPH, ACCR Editor-In-Chief, Associate Professor of Medicine, and Endocrine Neoplasia Specialist at Washington University School of Medicine, as they discuss the clinical case report, A Middle-aged Woman With Recurrent Intrathyroidal Parathyroid Cyst Treated With Ethanol Sclerotherapy, which presents a case of a recurrent intrathyroidal cyst successfully treated with ethanol sclerotherapy. Key topics discussed include the sclerosis efficacy in orthotopically positioned PCs, how ethanol sclerotherapy is an effective treatment option for recurrent intrathyroidal PCs, and important teaching points of this case. Visit https://www.aaceclinicalcasereports.com/article/S2376-0605(23)00131-1/fulltext to read the full AACE Clinical Case Report.